参考文献:抑郁治疗的脑机制。
抑郁   抑郁症   抑郁的治疗   

认知神经科学研究已经揭示了抑郁治疗的脑机制,研究成果刊发在Nature Reviews Neuroscience 上

抑郁症的认知疗法和药物疗法:治疗效果及神经机制

Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms

摘要:抑郁症是最普遍的精神疾病之一。最近研究表明:认知疗法与抗抑郁药物疗法对治疗抑郁症治愈率在16周后达到58%;一年内持续治疗药物治疗治愈率降到53%,认知疗法升至69%;停止治疗后,药物治疗只有46%未复发,认知治疗治愈率达到83%。在复发率上,治疗16周就停止药物76%再度复发,而停止使用认知疗法治疗后,复发率只有31%。认知疗法和药物疗法的某些神经机制可能是类似的,但另外一些机制可能彼此不同。对这些神经机制进行准确地说明,可能会在将来某一天指导治疗方法的选择和提高疗效。

Abstract

Depression is one of the most prevalent and debilitating of the psychiatric disorders. studies have shown that cognitive therapy is as efficacious as antidepressant medication at treating depression, and it seems to reduce the risk of relapse even after its discontinuation. Cognitive therapy and antidepressant medication probably engage some similar neural mechanisms, as well as mechanisms that are distinctive to each. A precise specification of these mechanisms might one day be used to guide treatment selection and improve outcomes.

文献下载:Cognitive therapy versus medication for depression: treatment outcomes and neural mechanisms Nature Reviews Neuroscience (2008) 9, 788-796.

 

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  • reniya 2013-2-20 12:07:41
    我觉得我还不算是那种严重的抑郁症,主要改变我的睡眠状态和家人的关系,我的问题不大
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